We demonstrate several applications of differentiating optimal solutions of constraint-based metabolic models, and show how it connects to classic metabolic control analysis
News
Drug synergies workflow successfully run on MareNostrum 4
PerMedCoE partners at Institut Curie and the University of Heidelberg developed a workflow that facilitates the prediction of personalised targeted drug combinations for cancer treatment, using CARNIVAL (Trairathphisan et al. 2021), PROFILE (Béal et al. 2019) and MaBoSS (Stoll et al. 2012, 2017) software. As a proof of concept, the workflow has successfully been run on the BSC MareNostrum 4 supercomputer.
Forthcoming webinars & courses
Our agenda of webinars and summer courses cover workflows management, intercellular interactions, and cell-level simulations.
PerMedCoE at the 21st European Conference on Computational Biology
PerMedCoE is attending the 21st European Conference on Computational Biology held in Sitges, Catalonia. This is where you can find our work: Posters 18th September - 13h to 14.30h Performance of multi-scale cell population simulators in different High-Performance...
Community-driven benchmarking hackathon
Researchers from European and North American universities will gather at the headquarters of the Barcelona Supercomputing Centre to compare tools simulating agent-based models used in biomedical projects.